Uremia

Methylguanidine

• John Doe
• Chronic Renal Failure, Uremia

5-Hydroxyindole (5-HI) is a metabolite produced by the conversion of 5-HTP by gut bacteria. A wide variety of gut bacteria can metabolize the dietary supplement and antidepressant 5-hydroxytryptophan (5-HTP) to 5-HI via the tryptophanase (TnaA) enzyme²